A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology.

A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology.

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Patient-derived tumor xenograft (PDX)/organoid (PDO), driven by cancer stem cells (CSC), are considered the most predictive models for translational oncology. Large PDX collections reflective of patient populations have been created and used extensively to test various investigational therapies, inc...

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Main Authors: Xiaoxi Xu, Rajendra Kumari, Jun Zhou, Jing Chen, Binchen Mao, Jingjing Wang, Meiling Zheng, Xiaolong Tu, Xiaoyu An, Xiaobo Chen, Likun Zhang, Xiaoli Tian, Haojie Wang, Xin Dong, Zhengzheng Bao, Sheng Guo, Xuesong Ouyang, Limei Shang, Fei Wang, Xuefei Yan, Rui Zhang, Robert G J Vries, Hans Clevers, Qi-Xiang Li
格式: 文件
语言:English
出版: Public Library of Science (PLoS) 2023-01-01
丛编:PLoS ONE
在线阅读:https://doi.org/10.1371/journal.pone.0279821

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https://doi.org/10.1371/journal.pone.0279821

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