Large depth-of-field ultra-compact microscope by progressive optimization and deep learning

Abstract The optical microscope is customarily an instrument of substantial size and expense but limited performance. Here we report an integrated microscope that achieves optical performance beyond a commercial microscope with a 5×, NA 0.1 objective but only at 0.15 cm3 and 0.5 g, whose size is fiv...

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Bibliographic Details
Main Authors: Yuanlong Zhang, Xiaofei Song, Jiachen Xie, Jing Hu, Jiawei Chen, Xiang Li, Haiyu Zhang, Qiqun Zhou, Lekang Yuan, Chui Kong, Yibing Shen, Jiamin Wu, Lu Fang, Qionghai Dai
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39860-0