Exploring Metabolic Signatures of Ex Vivo Tumor Tissue Cultures for Prediction of Chemosensitivity in Ovarian Cancer

Exploring Metabolic Signatures of Ex Vivo Tumor Tissue Cultures for Prediction of Chemosensitivity in Ovarian Cancer

Predicting patient response to treatment and the onset of chemoresistance are still major challenges in oncology. Chemoresistance is deeply influenced by the complex cellular interactions occurring within the tumor microenvironment (TME), including metabolic crosstalk. We have previously shown that...

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Bibliographic Details
Main Authors: Rita Mendes, Gonçalo Graça, Fernanda Silva, Ana C. L. Guerreiro, Patrícia Gomes-Alves, Jacinta Serpa, Erwin R. Boghaert, Paula M. Alves, Ana Félix, Catarina Brito, Inês A. Isidro
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
ovarian carcinoma
ex vivo models
tumor microenvironment
metabolomics
drug response
chemoresistance
Online Access:https://www.mdpi.com/2072-6694/14/18/4460

Internet

https://www.mdpi.com/2072-6694/14/18/4460

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