Novel murine model reveals an early role for pertussis toxin in disrupting neonatal immunity to Bordetella pertussis

The increased susceptibility of neonates to specific pathogens has previously been attributed to an underdeveloped immune system. More recent data suggest neonates have effective protection against most pathogens but are particularly susceptible to those that target immune functions specific to neon...

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Bibliographic Details
Main Authors: Colleen J. Sedney, Amanda Caulfield, Kaylan K. Dewan, Uriel Blas-Machado, Maiya Callender, Nancy R. Manley, Eric T. Harvill
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1125794/full