Development of stromal differentiation patterns in heterotypical models of artificial corneas generated by tissue engineering

Purpose: We carried out a histological characterization analysis of the stromal layer of human heterotypic cornea substitutes generated with extra-corneal cells to determine their putative usefulness in tissue engineering.Methods: Human bioartificial corneas were generated using nanostructured fibri...

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Main Authors: Cristina Blanco-Elices, Carmen Morales-Álvarez, Jesús Chato-Astrain, Carmen González-Gallardo, Paula Ávila-Fernández, Fernando Campos, Ramón Carmona, Miguel Ángel Martín-Piedra, Ingrid Garzón, Miguel Alaminos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1124995/full