Chicken speckle-type POZ protein (SPOP) negatively regulates MyD88/NF-κB signaling pathway mediated proinflammatory cytokine production to promote the replication of Newcastle disease virus

ABSTRACT: The speckle-type POZ protein (SPOP) is demonstrated to be a specific adaptor of the cullin-RING-based E3 ubiquitin ligase complex that participates in multiple cellular processes. Up to now, SPOP involved in inflammatory response has attracted more attention, but the association of SPOP wi...

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Bibliographic Details
Main Authors: Zhongming Meng, Yanbi Wang, Xianya Kong, Mona Cen, Zhiqiang Duan
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Poultry Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124000403