Effect of Diclofenac and Simvastatin on Bone Defect Healing—An In Vivo Animal Study

Non-steroidal, anti-inflammatory drugs and statins are two widely prescribed drug classes that affect bone formation. The aim of this study was to elucidate the effect of diclofenac and simvastatin in artificial bone defect healing. One hundred and forty-four male Wistar rats were used, and the spec...

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Bibliographic Details
Main Authors: Theodora Karanikola, Angeliki Cheva, Katia Sarafidou, Maria Myronidou-Tzouveleki, Ioannis Tsavdaridis, Eleana Kontonasaki, Anastasios Tsirlis
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomimetics
Subjects:
Online Access:https://www.mdpi.com/2313-7673/7/4/143