MITO-Luc/GFP zebrafish model to assess spatial and temporal evolution of cell proliferation in vivo

Abstract We developed a novel reporter transgenic zebrafish model called MITO-Luc/GFP zebrafish in which GFP and luciferase expression are under the control of the master regulator of proliferation NF-Y. In MITO-Luc/GFP zebrafish it is possible to visualize cell proliferation in vivo by fluorescence...

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Bibliographic Details
Main Authors: Luisa de Latouliere, Isabella Manni, Laura Ferrari, Federica Pisati, Maria Grazia Totaro, Aymone Gurtner, Emanuele Marra, Lucrezia Pacello, Ombretta Pozzoli, Luigi Aurisicchio, Maurizio C. Capogrossi, Gianluca Deflorian, Giulia Piaggio
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79530-5