Deubiquitination of MITF-M Regulates Melanocytes Proliferation and Apoptosis

Deubiquitination of MITF-M Regulates Melanocytes Proliferation and Apoptosis

Microphthalmia-associated transcription factor-M (MITF-M) is the key gene in the proliferation and differentiation of melanocytes, which undergoes an array of post-translation modifications. As shown in our previous study, deubiquitinase USP13 is directly involved in melanogenesis. However, it is st...

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Bibliographic Details
Main Authors: Shuaishuai Hu, Shaocheng Bai, Yingying Dai, Naisu Yang, Jiali Li, Xiyu Zhang, Fan Wang, Bohao Zhao, Guolian Bao, Yang Chen, Xinsheng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
MITF-M
melanocytes
USP13
deubiquitination
interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.692724/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.692724/full

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