The establishment and application of preimplantation genetic haplotyping in embryo diagnosis for reciprocal and Robertsonian translocation carriers

The establishment and application of preimplantation genetic haplotyping in embryo diagnosis for reciprocal and Robertsonian translocation carriers

Abstract Background Preimplantation genetic diagnosis (PGD) is now widely used to select embryos free of chromosomal copy number variations (CNV) from chromosome balanced translocation carriers. However, it remains a difficulty to distinguish in embryos between balanced and structurally normal chrom...

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Bibliographic Details
Main Authors: Shuo Zhang, Caixia Lei, Junping Wu, Jing Zhou, Haiyan Sun, Jing Fu, Yijuan Sun, Xiaoxi Sun, Daru Lu, Yueping Zhang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Medical Genomics
Subjects:
Single nucleotide polymorphism
Breakpoint
Preimplantation genetic haplotyping
Reciprocal translocation
Robertsonian translocation
Online Access:http://link.springer.com/article/10.1186/s12920-017-0294-x

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http://link.springer.com/article/10.1186/s12920-017-0294-x

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