Evaluation of high-throughput isomiR identification tools: illuminating the early isomiRome of Tribolium castaneum

Abstract Background MicroRNAs carry out post-transcriptional gene regulation in animals by binding to the 3' untranslated regions of mRNAs, causing their degradation or translational repression. MicroRNAs influence many biological functions, and dysregulation can therefore disrupt development o...

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Bibliographic Details
Main Authors: Daniel Amsel, Andreas Vilcinskas, André Billion
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1772-z