Regulation of the HIF switch in human endothelial and cancer cells

Regulation of the HIF switch in human endothelial and cancer cells

Hypoxia-inducible factors (HIFs) are transcription factors that reprogram the transcriptome for cells to survive hypoxic insults and oxidative stress. They are important during embryonic development and reprogram the cells to utilize glycolysis when the oxygen levels are extremely low. This metaboli...

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Bibliographic Details
Main Authors: Jakub Slawski, Maciej Jaśkiewicz, Anna Barton, Sylwia Kozioł, James F. Collawn, Rafał Bartoszewski
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:European Journal of Cell Biology
Subjects:
Hypoxia
Human endothelial cells
HIF1A
EPAS1
HIF3A
HIF-1α
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933524000037

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http://www.sciencedirect.com/science/article/pii/S0171933524000037

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