Impact of Siponimod on Enteric and Central Nervous System Pathology in Late-Stage Experimental Autoimmune Encephalomyelitis

Impact of Siponimod on Enteric and Central Nervous System Pathology in Late-Stage Experimental Autoimmune Encephalomyelitis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). Although immune modulation and suppression are effective during relapsing-remitting MS, secondary progressive MS (SPMS) requires neuroregenerative therapeutic options that act on the CNS. The sphingosine-1-phosphat...

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Bibliographic Details
Main Authors: Alicia Weier, Michael Enders, Philipp Kirchner, Arif Ekici, Marc Bigaud, Christopher Kapitza, Jürgen Wörl, Stefanie Kuerten
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
central nervous system
enteric nervous system
experimental autoimmune encephalomyelitis
fingolimod
multiple sclerosis
siponimod
Online Access:https://www.mdpi.com/1422-0067/23/22/14209

Internet

https://www.mdpi.com/1422-0067/23/22/14209

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