The Effects of Human Recombinant Il-1β on Rat Hepatic and Renal Cytochrome P450-Mediated Monooxygenase Activities
The effects of human recombinant IL-1β (BETALEUKIN) (6 × 10 4 – 6 × 10 6 U/Kg, intraperitoneally, single dose) on liver histology and cytochrome P450 (CYP450s)-mediated hepatic and renal monooxygenase activities were studied in adult male rats. rIL-1β (24 h after treatment) caused proinflammatory ch...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2004-05-01
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Series: | European Journal of Inflammation |
Online Access: | https://doi.org/10.1177/1721727X0400200202 |