Validation of a method for estimating pulmonary dead space in ventilated beagles to correct exhaled propofol concentration in mixed air

Validation of a method for estimating pulmonary dead space in ventilated beagles to correct exhaled propofol concentration in mixed air

Abstract Background Mixed exhaled air has been widely used to determine exhaled propofol concentrations with online analyzers, but changes in dead space proportions may lead to inaccurate assessments of critical drug concentration data. This study proposes a method to correct propofol concentration...

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Bibliographic Details
Main Authors: Xiaoxiao Li, Pan Chang, Xing Liu, Zhongjun Zhao, Yixiang Duan, Wensheng Zhang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Veterinary Research
Subjects:
Volumetric capnography
Dead space
Propofol
Vacuum ultraviolet time-of-flight mass spectrometry
Online analysis
Online Access:https://doi.org/10.1186/s12917-024-04458-1

Internet

https://doi.org/10.1186/s12917-024-04458-1

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