The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics

The SARS-CoV-2 spike glycoprotein interacts with MAO-B and impairs mitochondrial energetics

SARS-CoV-2 infection is associated with both acute and post-acute neurological symptoms. Emerging evidence suggests that SARS-CoV-2 can alter mitochondrial metabolism, suggesting that changes in brain metabolism may contribute to the development of acute and post-acute neurological complications. Mo...

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Bibliographic Details
Main Authors: Chantal A. Pileggi, Gaganvir Parmar, Hussein Elkhatib, Corina M. Stewart, Irina Alecu, Marceline Côté, Steffany A.L. Bennett, Jagdeep K. Sandhu, Miroslava Cuperlovic-Culf, Mary-Ellen Harper
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Neurobiology
Subjects:
SARS-CoV-2
Monoamine oxidase B
Mitochondria
Parkinson's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2665945X23000402

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http://www.sciencedirect.com/science/article/pii/S2665945X23000402

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