Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis

Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis

Abstract Demyelination and failure of remyelination in the central nervous system (CNS) characterize a number of neurological disorders. Spontaneous remyelination in demyelinating diseases is limited, as oligodendrocyte precursor cells (OPCs), which are often present in demyelinated lesions in abund...

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Bibliographic Details
Main Authors: Xiao-Yu Ji, Yu-Xin Guo, Li-Bin Wang, Wen-Cheng Wu, Jia-Qi Wang, Jin He, Rui Gao, Javad Rasouli, Meng-Yuan Gao, Zhen-Hai Wang, Dan Xiao, Wei-Feng Zhang, Bogoljub Ciric, Yuan Zhang, Xing Li
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Neuroinflammation
Subjects:
Demyelinating disease
OPCs
Microglia
Exosomes
miR-615-5p
Online Access:https://doi.org/10.1186/s12974-024-03019-5

Internet

https://doi.org/10.1186/s12974-024-03019-5

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