Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis

Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis

Abstract Demyelination and failure of remyelination in the central nervous system (CNS) characterize a number of neurological disorders. Spontaneous remyelination in demyelinating diseases is limited, as oligodendrocyte precursor cells (OPCs), which are often present in demyelinated lesions in abund...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Xiao-Yu Ji, Yu-Xin Guo, Li-Bin Wang, Wen-Cheng Wu, Jia-Qi Wang, Jin He, Rui Gao, Javad Rasouli, Meng-Yuan Gao, Zhen-Hai Wang, Dan Xiao, Wei-Feng Zhang, Bogoljub Ciric, Yuan Zhang, Xing Li
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2024-01-01
Σειρά:Journal of Neuroinflammation
Θέματα:
Demyelinating disease
OPCs
Microglia
Exosomes
miR-615-5p
Διαθέσιμο Online:https://doi.org/10.1186/s12974-024-03019-5

Διαδίκτυο

https://doi.org/10.1186/s12974-024-03019-5

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