Age-dependent changes in synaptic plasticity enhance tau oligomerization in the mouse hippocampus
Abstract The aggregation mechanism of phosphorylated tau is an important therapeutic target for tauopathies, including Alzheimer’s disease, although the mechanism by which aggregation occurs is still unknown. Because the phosphorylation process of tau is involved in the trafficking of AMPA receptors...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-09-01
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| Series: | Acta Neuropathologica Communications |
| Online Access: | http://link.springer.com/article/10.1186/s40478-017-0469-x |