An mRNA vaccine candidate encoding H5HA clade 2.3.4.4b protects mice from clade 2.3.2.1a virus infection

An mRNA vaccine candidate encoding H5HA clade 2.3.4.4b protects mice from clade 2.3.2.1a virus infection

Abstract Highly pathogenic avian influenza (HPAI) H5 viruses from different clades have been circulating globally, threatening wild/domestic birds and mammals. Given frequent spillovers and high mortality among mammals, coupled with our inability to predict which clade of H5 virus has pandemic poten...

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Bibliographic Details
Main Authors: Shiho Chiba, Maki Kiso, Shinya Yamada, Kazuhiko Someya, Yoshikuni Onodera, Aya Yamaguchi, Satoko Matsunaga, Ryuta Uraki, Kiyoko Iwatsuki-Horimoto, Seiya Yamayoshi, Fumihiko Takeshita, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00988-9

Internet

https://doi.org/10.1038/s41541-024-00988-9

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