The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strain.

Clostridium difficile is a major cause of healthcare-associated infection and inflicts a considerable financial burden on healthcare systems worldwide. Disease symptoms range from self-limiting diarrhoea to fatal pseudomembranous colitis. Whilst C. difficile has two major virulence factors, toxin A...

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Bibliographic Details
Main Authors: Soza T Baban, Sarah A Kuehne, Amira Barketi-Klai, Stephen T Cartman, Michelle L Kelly, Kim R Hardie, Imad Kansau, Anne Collignon, Nigel P Minton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781105?pdf=render