The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strain.
Clostridium difficile is a major cause of healthcare-associated infection and inflicts a considerable financial burden on healthcare systems worldwide. Disease symptoms range from self-limiting diarrhoea to fatal pseudomembranous colitis. Whilst C. difficile has two major virulence factors, toxin A...
Main Authors: | Soza T Baban, Sarah A Kuehne, Amira Barketi-Klai, Stephen T Cartman, Michelle L Kelly, Kim R Hardie, Imad Kansau, Anne Collignon, Nigel P Minton |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3781105?pdf=render |
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