Modeling of Personalized Treatments in Colon Cancer Based on Preclinical Genomic and Drug Sensitivity Data

Modeling of Personalized Treatments in Colon Cancer Based on Preclinical Genomic and Drug Sensitivity Data

The current standard therapies for advanced, recurrent or metastatic colon cancer are the 5-fluorouracil and oxaliplatin or irinotecan schedules (FOxFI) +/− targeted drugs cetuximab or bevacizumab. Treatment with the FOxFI cytotoxic chemotherapy regimens causes significant toxicity and might induce...

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Bibliographic Details
Main Authors: Marlen Keil, Theresia Conrad, Michael Becker, Ulrich Keilholz, Marie-Laure Yaspo, Hans Lehrach, Moritz Schütte, Johannes Haybaeck, Jens Hoffmann
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
colon cancer
personalized treatment
drug combinations
Online Access:https://www.mdpi.com/2072-6694/13/23/6018

Internet

https://www.mdpi.com/2072-6694/13/23/6018

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