A Retrospective Study on the Role of Metformin in Colorectal Cancer Liver Metastases

Colorectal cancer liver metastases (CRCLMs) have two main histopathological growth patterns (HPGs): desmoplastic (DHGP) and replacement (RHGP). The vascularization in DHGP tumours is angiogenic, while the RHGP tumours exert vessel co-option vasculature. The presence of vessel co-option tumours is as...

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Bibliographic Details
Main Authors: Miran Rada, Lucyna Krzywon, Stephanie Petrillo, Anthoula Lazaris, Peter Metrakos
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/3/731