Neurexin and neuroligins jointly regulate synaptic degeneration at the Drosophila neuromuscular junction based on TEM studies

Neurexin and neuroligins jointly regulate synaptic degeneration at the Drosophila neuromuscular junction based on TEM studies

The Drosophila larval neuromuscular junction (NMJ) is a well-known model system and is often used to study synapse development. Here, we show synaptic degeneration at NMJ boutons, primarily based on transmission electron microscopy (TEM) studies. When degeneration starts, the subsynaptic reticulum (...

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Bibliographic Details
Main Authors: Gan Guangming, Chen Mei, Yu Qinfeng, Gao Xiang, Zhang Chenchen, Sheng Qingyuan, Xie Wei, Geng Junhua
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Drosophila
neuromuscular junction
synaptic degeneration
neurexin
neuroligins
transmission electron microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1257347/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1257347/full

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