Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process

Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process

Red blood cells (RBCs) can act as carriers for therapeutic agents and can substantially improve the safety, pharmacokinetics, and pharmacodynamics of many drugs. Maintaining RBCs integrity and lifespan is important for the efficacy of RBCs as drug carrier. We investigated the impact of drug encapsul...

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Bibliographic Details
Main Authors: Mélanie Robert, Bastien Laperrousaz, Diana Piedrahita, Emilie-Fleur Gautier, Travis Nemkov, Florian Dupuy, Elie Nader, Virginie Salnot, Patrick Mayeux, Angelo D'Alessandro, Catherine Lavazec, Philippe Joly, Alexander Scheer, Philippe Connes, Agnès Cibiel
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Red blood cells
Drug carrier
Hypotonic dialysis
l-Asparaginase
Omics
Rheology
Online Access:http://www.sciencedirect.com/science/article/pii/S221138352100410X

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http://www.sciencedirect.com/science/article/pii/S221138352100410X

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