The Neurodevelopmental and Molecular Landscape of Medulloblastoma Subgroups: Current Targets and the Potential for Combined Therapies

The Neurodevelopmental and Molecular Landscape of Medulloblastoma Subgroups: Current Targets and the Potential for Combined Therapies

Medulloblastoma is the most common malignant pediatric brain tumor and is associated with significant morbidity and mortality in the pediatric population. Despite the use of multiple therapeutic approaches consisting of surgical resection, craniospinal irradiation, and multiagent chemotherapy, the p...

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Bibliographic Details
Main Authors: Hasan Slika, Paolo Alimonti, Divyaansh Raj, Chad Caraway, Safwan Alomari, Eric M. Jackson, Betty Tyler
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cancers
Subjects:
medulloblastoma subgroups
molecular pathways
targeted therapy
combination therapy
neurodevelopmental origin
pediatric brain tumors
Online Access:https://www.mdpi.com/2072-6694/15/15/3889

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https://www.mdpi.com/2072-6694/15/15/3889

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