The breast cancer immune microenvironment is modified by neoadjuvant chemotherapy

Abstract Neoadjuvant chemotherapy (NAT) in breast cancer (BC) has been used to reduce tumor burden prior to surgery. However, the impact on prognosis depends on the establishment of Pathological Complete Response (pCR), which is influenced by tumor-infiltrating lymphocyte levels and the activation o...

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Bibliographic Details
Main Authors: Claudia Urueña, Paola Lasso, David Bernal-Estevez, Diego Rubio, Ana Janeth Salazar, Mercedes Olaya, Alfonso Barreto, Mauricio Tawil, Lilian Torregrosa, Susana Fiorentino
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12108-5