Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome

Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome

A large EEG dataset from 70 patients with Fragile X syndrome reveals unique changes in neural activity and highlight the role for disrupted thalamocortical modulation in local hyperexcitability.

Bibliographic Details
Main Authors: Ernest V. Pedapati, Lauren M. Schmitt, Lauren E. Ethridge, Makoto Miyakoshi, John A. Sweeney, Rui Liu, Elizabeth Smith, Rebecca C. Shaffer, Kelli C. Dominick, Donald L. Gilbert, Steve W. Wu, Paul S. Horn, Devin K. Binder, Martine Lamy, Megan Axford, Craig A. Erickson
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03395-9

Internet

https://doi.org/10.1038/s42003-022-03395-9

Similar Items