Anthraquinones as Inhibitors of SOS RAS-GEF Activity

Anthraquinones as Inhibitors of SOS RAS-GEF Activity

Recent breakthroughs have reignited interest in RAS GEFs as direct therapeutic targets. To search for new inhibitors of SOS GEF activity, a repository of known/approved compounds (NIH-NACTS) and a library of new marine compounds (Biomar Microbial Technologies) were screened by means of in vitro RAS-...

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Bibliografiska uppgifter
Huvudupphovsmän: Alberto Fernández-Medarde, Rocío Fuentes-Mateos, Rósula García-Navas, Andrea Olarte-San Juan, José María Sánchez-López, Antonio Fernández-Medarde, Eugenio Santos
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2021-07-01
Serie:Biomolecules
Ämnen:
anthraquinones
SOS
RAS-GEF
inhibitors
cancer
Länkar:https://www.mdpi.com/2218-273X/11/8/1128

Internet

https://www.mdpi.com/2218-273X/11/8/1128

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