Mg-ZIF nanozyme regulates the switch between osteogenic and lipogenic differentiation in BMSCs via lipid metabolism

Mg-ZIF nanozyme regulates the switch between osteogenic and lipogenic differentiation in BMSCs via lipid metabolism

Abstract The accumulation of reactive oxygen species (ROS) within the bone marrow microenvironment leads to diminished osteogenic differentiation and heightened lipogenic differentiation of mesenchymal stem cells residing in the bone marrow, ultimately playing a role in the development of osteoporos...

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Bibliographic Details
Main Authors: Jinying Li, Yongshao Chen, Dingsheng Zha, Chunhui Wu, Xiaofen Li, Li Yang, Hui Cao, Shexing Cai, Yuebo Cai
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Lipids in Health and Disease
Subjects:
Mg-ZIF nanozyme
Osteogenic differentiation
Lipid metabolism
ROS
BMSCs
Osteoporosis
Online Access:https://doi.org/10.1186/s12944-024-02083-3

Internet

https://doi.org/10.1186/s12944-024-02083-3

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