Syndecan 4 Upregulation on Activated Langerhans Cells Counteracts Langerin Restriction to Facilitate Hepatitis C Virus Transmission

Syndecan 4 Upregulation on Activated Langerhans Cells Counteracts Langerin Restriction to Facilitate Hepatitis C Virus Transmission

Sexually transmitted Hepatitis C virus (HCV) infections and high reinfections are a major concern amongst men who have sex with men (MSM) living with HIV-1 and HIV-negative MSM. Immune activation and/or HIV-1 coinfection enhance HCV susceptibility via sexual contact, suggesting that changes in immun...

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Bibliographic Details
Main Authors: Bernadien M. Nijmeijer, Julia Eder, Catharina J. M. Langedijk, Tanja M. Kaptein, Sofie Meeussen, Pascale Zimmermann, Carla M. S. Ribeiro, Teunis B. H. Geijtenbeek
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
langerhans cells
hepatitis C virus
heparan sulfate proteoglycans
heparan sulfates
syndecan 4
langerin
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00503/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00503/full

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