Hsp60 Chaperonin Acts as Barrier to Pharmacologically Induced Oxidative Stress Mediated Apoptosis in Tumor Cells with Differential stress Response
Mitochondrial functions play a central role in energy metabolism and provide survival fitness to both normal and tumor cells. Mitochondrial chaperonin Hsp60 is involved in both pro- and anti-apoptotic functions, but how Hsp60 senses the mitochondria selective oxidative stress response is unknown. In...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
AboutScience Srl
2013-01-01
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Series: | Drug Target Insights |
Online Access: | https://doi.org/10.4137/DTI.S12513 |