Hemodynamic changes and neuronal damage detected by 9.4 T MRI in rats with chronic cerebral ischemia and cognitive impairment

Abstract Introduction The bilateral common carotid artery occlusion (BCCAO) rat model is an ideal animal model for simulating the pathology of chronic brain hypoperfusion in humans. However, dynamic changes in neuronal activity, cellular edema, and neuronal structural integrity in vivo after BCCAO h...

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Bibliographic Details
Main Authors: Minghua Sun, Liangmiao Wu, Guangying Chen, Xukai Mo, Changzheng Shi
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.2642