Investigating the impact of antibiotic-induced dysbiosis on protection from Clostridium difficile colitis by mouse colonic innate lymphoid cells

Investigating the impact of antibiotic-induced dysbiosis on protection from Clostridium difficile colitis by mouse colonic innate lymphoid cells

ABSTRACT Innate lymphoid cells (ILCs) play a critical role in maintaining intestinal health in homeostatic and diseased conditions. During Clostridium difficile infection (CDI), IL-33 activates ILC2 to protect from colonic damage and mortality. The function of IL-33 and ILC is tightly regulated by t...

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Bibliographic Details
Main Authors: Md Jashim Uddin, Brandon Thompson, Jhansi L. Leslie, Casey Fishman, Katia Sol-church, Pankaj Kumar, William A. Petri
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:mBio
Subjects:
Clostridioides difficile
innate lymphoid cells
colitis
single-cell RNAseq
host immune response
Online Access:https://journals.asm.org/doi/10.1128/mbio.03338-23

Internet

https://journals.asm.org/doi/10.1128/mbio.03338-23

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