Oncolytic therapy with vaccinia virus carrying IL-24 for hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) is a highly refractory cancer associated with increasing mortality, which currently lacks effective treatment options. Interleukin-24 (IL-24) is a novel tumor suppressor cytokine that can selectively induce cancer cell apoptosis, and it has been uti...

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Bibliographic Details
Main Authors: Lili Deng, Xue Yang, Yuedi Ding, Jun Fan, Ying Peng, Dong Xu, Biao Huang, Zhigang Hu
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-022-01779-1