Targeting Microglia/Macrophages Notch1 Protects Neurons from Pyroptosis in Ischemic Stroke

Targeting Microglia/Macrophages Notch1 Protects Neurons from Pyroptosis in Ischemic Stroke

Background and Aims: The immune-inflammatory cascade and pyroptosis play an important role in the pathogenesis of cerebral ischemia-reperfusion injury (CIRI). The maintenance of immune homeostasis is inextricably linked to the Notch signaling pathway, but whether myeloid Notch1 affects microglia pol...

Full description

Bibliographic Details
Main Authors: Ran Chen, Hua Zhu, Zhihui Wang, Yonggang Zhang, Jin Wang, Yingao Huang, Lijuan Gu, Changyong Li, Xiaoxing Xiong, Zhihong Jian
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Brain Sciences
Subjects:
ischemic stroke
pyroptosis
neuroinflammation
Notch1
CIRI
Online Access:https://www.mdpi.com/2076-3425/13/12/1657

Internet

https://www.mdpi.com/2076-3425/13/12/1657

Similar Items