Induced Pluripotent Stem Cell-Derived Monocytes/Macrophages in Autoinflammatory Diseases

Induced Pluripotent Stem Cell-Derived Monocytes/Macrophages in Autoinflammatory Diseases

The concept of autoinflammation, first proposed in 1999, refers to a seemingly unprovoked episode of sterile inflammation manifesting as unexplained fever, skin rashes, and arthralgia. Autoinflammatory diseases are caused mainly by hereditary abnormalities of innate immunity, without the production...

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Bibliographic Details
Main Authors: Takayuki Tanaka, Takeshi Shiba, Yoshitaka Honda, Kazushi Izawa, Takahiro Yasumi, Megumu K. Saito, Ryuta Nishikomori
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
autoinflammatory diseases
induced pluripotent stem cells
disease modeling
drug screening
monocytes
macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.870535/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.870535/full

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