Circulating levels and the bioactivity of miR-30b increase during pubertal progression in boys

BackgroundPuberty marks the transition from childhood to adulthood and is initiated by activation of a pulsatile GnRH secretion from the hypothalamus. MKRN3 functions as a pre-pubertal break on the GnRH pulse generator and hypothalamic expression and circulating levels of MKRN3 decrease peri-puberta...

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Bibliographic Details
Main Authors: Nina Mørup, Rytis Stakaitis, Ailsa Maria Main, Ieva Golubickaite, Casper P. Hagen, Anders Juul, Kristian Almstrup
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1120115/full