Gut microbial structural variation associates with immune checkpoint inhibitor response

Abstract The gut microbiota may have an effect on the therapeutic resistance and toxicity of immune checkpoint inhibitors (ICIs). However, the associations between the highly variable genomes of gut bacteria and the effectiveness of ICIs remain unclear, despite the fact that merely a few gene mutati...

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Bibliographic Details
Main Authors: Rong Liu, You Zou, Wei-Quan Wang, Jun-Hong Chen, Lei Zhang, Jia Feng, Ji-Ye Yin, Xiao-Yuan Mao, Qing Li, Zhi-Ying Luo, Wei Zhang, Dao-Ming Wang
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42997-7