3D models in the new era of immune oncology: focus on T cells, CAF and ECM

3D models in the new era of immune oncology: focus on T cells, CAF and ECM

Abstract Immune checkpoint inhibitor therapy has changed clinical practice for patients with different cancers, since these agents have demonstrated a significant improvement of overall survival and are effective in many patients. However, an intrinsic or acquired resistance frequently occur and bio...

Full description

Bibliographic Details
Main Authors: Francesca Di Modugno, Cristina Colosi, Paola Trono, Giuseppe Antonacci, Giancarlo Ruocco, Paola Nisticò
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Tumor microenvironment
Immune oncology
3D culture models
T cells
Cancer associated fibroblasts
Extracellular matrix
Online Access:http://link.springer.com/article/10.1186/s13046-019-1086-2

Internet

http://link.springer.com/article/10.1186/s13046-019-1086-2

Similar Items