Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior

<p>Abstract</p> <p>Background</p> <p>Investigations of nucleotide signaling in nociception to date have focused on actions of adenosine triphosphate (ATP). Both ATP-gated ion channels (P2X receptors) and G protein-coupled (P2Y) receptors contribute to nociceptive signal...

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Bibliographic Details
Main Authors: Molliver Derek C, Malin Sacha A
Format: Article
Language:English
Published: SAGE Publishing 2010-04-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/6/1/21