Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts

<p>Abstract</p> <p>Introduction</p> <p>Tumour phenotype is regulated in a complex fashion as a result of interactions between malignant cells and the tumour stroma. Fibroblasts are the most abundant and perhaps most active part of the tumour stroma. A better understandi...

Full description

Bibliographic Details
Main Authors: Olsen Charlotta J, Moreira José, Lukanidin Eugene M, Ambartsumian Noona S
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/444