Evolution of the complex transcription network controlling biofilm formation in Candida species

We examine how a complex transcription network composed of seven ‘master’ regulators and hundreds of target genes evolved over a span of approximately 70 million years. The network controls biofilm formation in several Candida species, a group of fungi that are present in humans both as constituents...

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Bibliographic Details
Main Authors: Eugenio Mancera, Isabel Nocedal, Stephen Hammel, Megha Gulati, Kaitlin F Mitchell, David R Andes, Clarissa J Nobile, Geraldine Butler, Alexander D Johnson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/64682