The role of LCN2 and LCN2-MMP9 in spondylitis radiographic development: gender and HLA-B27 status differences

The role of LCN2 and LCN2-MMP9 in spondylitis radiographic development: gender and HLA-B27 status differences

Abstract Background Male HLA-B27-positive radiographic-axial spondyloarthritis (r-axSpA) patients are prone to have severe spinal radiographic progression, but the underlying mechanisms are unclear. We recently showed that persistently elevated Lipocalin 2 (LCN2; L) reflects sacroiliac joint (SIJ) i...

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Bibliographic Details
Main Authors: Florence W. L. Tsui, Aifeng Lin, Ismail Sari, Zhenbo Zhang, Kenneth P. H. Pritzker, Hing Wo Tsui, Robert D. Inman
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Arthritis Research & Therapy
Subjects:
Axial spondyloarthritis
Lipocalin 2
Lipocalin 2-MMP9 complex
MRI
SIJ and spinal inflammation
mSASSS
Online Access:https://doi.org/10.1186/s13075-022-02854-2

Internet

https://doi.org/10.1186/s13075-022-02854-2

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