Pembrolizumab in the treatment of locally advanced or metastatic urothelial carcinoma: clinical trial evidence and experience

The treatment of advanced urothelial carcinoma (UC) has dramatically changed with the advent of immune checkpoint inhibitors that disrupt the T-cell inhibitory interaction between the programmed cell death (PD)-1 receptor and its ligand (PD-L1). Pembrolizumab, a highly specific, monoclonal antibody...

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Bibliographic Details
Main Authors: Michael Crist, Gopa Iyer, Miles Hsu, William C. Huang, Arjun V. Balar
Format: Article
Language:English
Published: SAGE Publishing 2019-04-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/1756287219839285