L type Ca<sup>2+ </sup>channel blockers prevent oxaliplatin-induced cold hyperalgesia and TRPM8 overexpression in rats

<p>Abstract</p> <p>Background</p> <p>Oxaliplatin is an important drug used in the treatment of colorectal cancer. However, it frequently causes severe acute and chronic peripheral neuropathies. We recently reported that repeated administration of oxaliplatin induced col...

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Bibliographic Details
Main Authors: Kawashiri Takehiro, Egashira Nobuaki, Kurobe Kentaro, Tsutsumi Kuniaki, Yamashita Yuji, Ushio Soichiro, Yano Takahisa, Oishi Ryozo
Format: Article
Language:English
Published: SAGE Publishing 2012-01-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/8/1/7