Disseminated tuberculosis, CMV viraemia & haemophagocytic-lymphohistiocystosis syndrome in an adult patient with anti- IFNγ autoantibodies – case report and brief review

Disseminated tuberculosis, CMV viraemia & haemophagocytic-lymphohistiocystosis syndrome in an adult patient with anti- IFNγ autoantibodies – case report and brief review

We report a case of an adult female with disseminated tuberculosis, cytomegalovirus viraemia and haemophagocytic-lymphohistiocystosis syndrome associated with neutralizing anti- interferon gamma (IFNγ) autoantibodies demonstrated by absent IFNγ stimulated STAT1 phosphorylation in the presence of pat...

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Bibliographic Details
Main Authors: G.I. Butel-Simoes, C. Kiss, K. Kong, L.B. Rosen, L.M. Hosking, S. Barnes, G.A. Jenkin, S. Megaloudis, B. Kumar, S.M. Holland, S. Ojaimi
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Clinical Immunology Communications
Subjects:
Anti-interferon gamma autoantibodies
Tuberculosis
Haemophagocytic lymphohistiocytosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2772613423000240

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http://www.sciencedirect.com/science/article/pii/S2772613423000240

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