Anticonvulsant, hypnotic and muscle relaxant effects of carbenoxolone, the synthetic constituent of licorice in mice

The anticonvulsant, hypnotic and muscle relaxant effects of carbenoxolone were studied in mice. In pentylenetetrazole test ED50 values of diazepam and carbenoxolone were 1.13 mg/kg (95% CL: 0.89-1.44) and 283.3 mg/kg (95% CL: 144.27-556.29), respectively. In this test, carbenoxolone in doses of 200...

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Bibliographic Details
Main Authors: Asl M Nassiri, H Hosseinzadeh
Format: Article
Language:English
Published: Institue of Medicinal Plants, ACECR 2003-03-01
Series:Journal of Medicinal Plants
Subjects:
Online Access:http://jmp.ir/article-1-784-en.html