PDGFRA Is Not Essential for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines

PDGFRA Is Not Essential for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines

Extraembryonic endoderm stem (XEN) cell lines can be derived and maintained in vitro and reflect the primitive endoderm lineage. Platelet-derived growth factor receptor alpha (PDGFRA) is thought to be essential for the derivation and maintenance of mouse XEN cell lines. Here, we have re-evaluated th...

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Bibliographic Details
Main Authors: Jiangwei Lin, Mona Khan, Bolek Zapiec, Peter Mombaerts
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Stem Cell Reports
Subjects:
XEN
primitive endoderm
Pdgfra
Sox17
postimplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117303624

Internet

http://www.sciencedirect.com/science/article/pii/S2213671117303624

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